Dihydrotestosterone (DHT) is an androgenic hormone that produces a stronger form of testosterone It represents a crucial role in the development of male sexual characteristics during the puberty, including the development of male sex organs, body hair, and a deeper voice. DHT is produced by the conversion of testosterone by the enzyme 5-alpha reductase, which is present in various tissues of the body, including the skin, prostate, and hair follicles.
Although DHT is important for male development, it is also associated with androgenetic atrophy Alopecia (associated with hereditary hair loss). In genetically predisposed individuals, DHT can lead to.. Hair follicles shrink or “miniaturize”. This process shortens the growth phase (Anagen phase) of the hair and causes the new hairs to become thinner and shorter, until finally no new hair grows.
DHT also plays an important role in the development and enlargement of the prostate. An excess of DHT has been associated with benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate that can cause problems with urinary flow and other urine-related symptoms.
To minimize the effects of DHT on hair loss and prostate enlargement, medications are often used that inhibit the activity of 5-alpha reductase and thus reduce the conversion of testosterone to DHT. These medications include:
While treatment with 5-alpha reductase inhibitors is effective for many men, it can also have side effects, including sexual dysfunction, decreased libido, and, in rare cases, breast enlargement or tenderness. The decision to undergo such treatment should always be made in consultation with a doctor who will weigh the potential benefits against the possible risks.
There are also natural substances and foods that can act as DHT blockers, such as saw palmetto, pumpkin seeds, and green tea. Although these natural remedies are a popular choice for those seeking alternative treatments, their effectiveness is less well-documented compared to medical therapies.
In summary, DHT is an important hormone in the human body, but excessive production or sensitivity can lead to problems such as hair loss and prostate enlargement. Treatment aims to reduce the production or effects of DHT in order to manage these conditions.
